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James L. Flanagang from studies of phenomena as diverse as planetary climates, crystal growth morphology, bacterial metabolism and photosynthesis. And yet MEP is still regarded by many as nothing other than a curiosity, largely because a theoretical justification for it has been lacking. This chapter offers a non-ma使高兴 发表于 2025-3-22 08:31:18
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James L. Flanaganuss different diseases associated with protein misfolding anAmyloid-forming proteins are implicated in over 30 human diseases. The proteins involved in each disease have unrelated sequences and dissimilar native structures, but they all undergo conformational alterations to form fibrillar polymers.泥沼 发表于 2025-3-22 18:04:15
James L. Flanagane structures, but they all undergo conformational alterations to form fibrillar polymers. The fibrillar assemblies accumulate progressively into disease-specific lesions in vivo. Substantial evidence suggests these lesions are the end state of aberrant protein folding whereas the actual disease-caus壮观的游行 发表于 2025-3-22 21:35:58
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