MOAT
发表于 2025-3-23 13:22:25
Barbara Brokampes and practice of stereotactic body radiotherapy (SBRT) for treatment of stage I NSCLC are summarized. This radiotherapy concept, where millimeter accuracy of radiotherapy allowed irradiation with very high irradiation doses, consistently achieves local tumor control in >90 % of the patients. Simul
candle
发表于 2025-3-23 15:46:03
Mara Westling Allodi.g., KRAS mutations, MET amplification), or germline alteration of proapoptotic proteins. Secondary resistance is mediated by T790M mutation in 50–60 % of cases. Further mechanisms are alternative pathway activation and kinase switching or histologic transformation. New treatment options in acquired
Antarctic
发表于 2025-3-23 19:26:55
the antigen be processed by specialized cells, the so called antigen-presenting cells (APC), which include, among others, the monocyte/macrophage. However, T cell recognition of the antigen is restricted by the expression of surface molecules coded by the major histocompatibility complex (MHC) genes
diskitis
发表于 2025-3-23 23:00:18
Pasquale Andreozzi,Anna Pietrocarlothe antigen be processed by specialized cells, the so called antigen-presenting cells (APC), which include, among others, the monocyte/macrophage. However, T cell recognition of the antigen is restricted by the expression of surface molecules coded by the major histocompatibility complex (MHC) genes
保守
发表于 2025-3-24 05:31:01
Clara Diletta Favellaombination with methotrexate, use in moderate rather than severe disease, tight control as well as induration and maintenance regimes. Despite therapeutic advances with target therapies a number of unmet needs exist, including a low remission rate, cost and inadequate access as well as the lack of b
闲逛
发表于 2025-3-24 07:24:44
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Pde5-Inhibitors
发表于 2025-3-24 14:06:52
Fabio Dovigo,Francesca Gaspariniare represented by superficial spreading melanomas, and high-CSD melanomas include lentigo maligna and desmoplastic melanomas. In the category with low or no sun exposure, acral melanomas, melanomas in congenital or blue nevi, Spitz melanomas, mucosal melanomas, and uveal melanomas are incorporated.
薄荷醇
发表于 2025-3-24 17:44:49
Emanuela Zappella extremely useful in unveiling the mutation landscapes in driver genes and pathways. Putting together all recent data, the melanoma pathogenesis scenario appears to be highly more complicated than hypothesized before. A molecular classification strategy based on such in-depth knowledge is becoming m
支架
发表于 2025-3-24 20:26:31
in cell cycle control (., .), signalling (., .) and differentiation (., .) are often altered in SCCs. In Merkel cell carcinomas (MCCs) mutations occur in ., ., . and in the PI3K-AKT pathway genes. Aberrations in MCCs result from UV exposure as well as Merkel cell polyomavirus infection. It is worth
ACRID
发表于 2025-3-25 02:16:50
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