GNAW 发表于 2025-3-23 10:27:04

Ibrutinib,is chapter discusses structure, mechanism of action, and toxicities of ibrutinib and also presents important preclinical and clinical data. Phase III trials will have to determine the definite role of ibrutinib in clinical practice but the data available so far suggests it may be a powerful new weapon in the battle against B-cell malignancies.

控制 发表于 2025-3-23 17:22:18

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AGGER 发表于 2025-3-23 21:46:03

5-Azacytidine/5-Azacitidine,treatment of choice. Preliminary data on combinations of the hypomethylating agent with other new drugs are promising, and innovative strategies involving immune modulation and regenerative tissue repair hold a broad potential for future developments.

corpuscle 发表于 2025-3-23 23:08:28

Imatinib Mesylate, of anticancer agents, so-called small molecules. They have a high selectivity against a specific molecular target known to be the cause for the establishment and maintenance of the malignant phenotype. Imatinib is a rationally designed oral signal transduction inhibitor that specifically targets se

Innovative 发表于 2025-3-24 05:35:35

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兽皮 发表于 2025-3-24 10:36:28

Nilotinib,e of the most striking achievements in modern cancer medicine. However, while imatinib can establish long-term remission in many cases, resistance to or intolerance of imatinib is eventually experienced by a substantial number of patients. Subsequent advances have led to the development of novel tyr

好色 发表于 2025-3-24 14:36:27

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Champion 发表于 2025-3-24 16:05:54

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molest 发表于 2025-3-24 22:01:30

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得意人 发表于 2025-3-24 23:41:22

Lapatinib, and gastric cancer, and maybe also additional tumor types, HER2 and its homo- or heterodimerization with HER1 or HER3 are essential for cancer cell growth and survival. Breast cancer patients overexpressing HER2 have a poor prognosis, which can be substantially improved upon HER2-targeted therapy u
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查看完整版本: Titlebook: Small Molecules in Oncology; Uwe M. Martens Book 2014Latest edition Springer-Verlag Berlin Heidelberg 2014 Molecular mechanisms of cancer.