Neogamist 发表于 2025-3-21 16:53:57
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Creating Knowledge from High-Throughput Screening Data, or the application of conventional data analysis techniques is no viable option for logistical reasons. Hence, there is much current interest in novel analytical approaches that support the many facets of data analysis in HTS.压碎 发表于 2025-3-22 20:46:06
Target Analysis: A Priori Assessment of Druggability,ity” as the ability of a target to be modulated by potent, small “drug-like” molecules (which are often suitable for oral delivery). The physico-chemical properties of “drug-like” molecules are discussed below. In turn, the “druggability” of a target can be assessed from analysis of all the availablcalamity 发表于 2025-3-22 22:52:32
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Chemical Genomics of Orphan Nuclear Receptors,sdorf et al. 1995). These nuclear hormone receptors contain two signature domains, a central double zinc finger DNA-binding domain (DBD) and a C-terminal ligand-binding domain (LBD) (Fig. 1). Sequence homology within these domains has allowed investigators to clone many additional members of the gen有花 发表于 2025-3-23 08:09:00
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