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1568-2102 ys achieve.Encouraging potential clinical applications for pThe poor prognosis and high mortality for cancer patients are majorly ascribed to tumor metastasis, one of the most complicated pathological processes. Elucidation of molecular mechanisms for metastasis is essential for management and preve鲁莽 发表于 2025-3-22 12:01:34
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Notch Signaling in Cancer Metastasis,n, tumor angiogenesis, and the formation and maintenance of cancer stem cells (or cancer initiating cells). In this chapter, we will review the molecular, cellular and phenotypic effects of Notch signaling on a wide range of cancers and how these contribute to tumor metastasis.exclamation 发表于 2025-3-22 20:48:01
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Overview of Signal Transduction in Tumor Metastasis, environment may trigger epithelial–mesenchymal transition (EMT), migration and invasion of the primary tumor via integration of multiple pathways. Further, TGF-β1/Smad signaling may switch the tumor cell from cohesive to single cell movement that facilitates the invasive tumor to enter blood circul预示 发表于 2025-3-23 02:10:23
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