碳水化合物
发表于 2025-3-25 04:32:34
Book 2017 treatments for blinding retinal diseases emphasize the tremendous far-reaching potential for ligands for these receptors. Exciting breakthroughs in this dynamic field in the last decade are reported herein, which will guide future investigators in determining the full potential of this unique, yet abundantly expressed protein..
悠然
发表于 2025-3-25 07:55:55
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确定无疑
发表于 2025-3-25 12:55:25
Structural Perspectives on Sigma-1 Receptor Function,each protomer binds a single ligand molecule at the center of its carboxy-terminal domain. These results offer detailed molecular views of receptor structure, oligomerization, and ligand recognition, providing a framework for the next era of sigma-1 research.
把…比做
发表于 2025-3-25 16:52:35
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AROMA
发表于 2025-3-25 20:56:52
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GEST
发表于 2025-3-26 03:54:47
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含糊其辞
发表于 2025-3-26 06:33:03
Sigma Receptors and Substance Use Disorders, including cocaine, methamphetamine, and alcohol. The present chapter will review the current scientific knowledge on the role of the Sigma Receptor system in the effects of drugs and alcohol, and proposes that this receptor system may represent a novel therapeutic target for the treatment of substance use disorders and associated neurotoxicity.
Conquest
发表于 2025-3-26 08:45:24
0065-2598 f significant relevance to very severe diseases (blindness, .Originally confused with opioid receptors and then orphan receptors with no biological function, Sigma Receptors are now recognized as relevant to many degenerative diseases with remarkable potential as therapeutic targets. In this text, n
我不怕牺牲
发表于 2025-3-26 15:04:30
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acheon
发表于 2025-3-26 18:18:39
Stimulation of the Sigma-1 Receptor and the Effects on Neurogenesis and Depressive Behaviors in Mic B (Akt) activities in hippocampus. Therefore, we discuss the fundamental roles of Sig-1R, CaMKII/CaMKIV and protein kinase B (Akt) signaling in amelioration of depressive-like behaviors following Sig-1R stimulation.