morphology 发表于 2025-3-21 17:06:24
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Novel Approaches to Serotonin Receptor Interaction Studies participate in a wide range of signal transduction pathways. Alterations of their activities often occur in pathological and psychopathological disorders. Therefore, these receptors determine major targets for drug discovery. Currently, the concept of GPCR oligomerization has become widely acceptedIrrepressible 发表于 2025-3-22 05:42:24
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Organotypic Slices and Biolistic Transfection for the Study of Serotonin Receptor Function in CNS Neadvantages of isolated in vitro experimental preparations with preservation of key aspects of the neuronal anatomy and physiology seen in whole animals. Acutely prepared slices have proven very useful for the study of serotonin (5-HT) signaling in the CNS, and neuronal signaling in general. The usefhabile 发表于 2025-3-22 16:17:34
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The Murine Serotonin Syndrome and the 5-HT1A Receptor: Behavioral Effects and Hypothermiae agonists at 5-HT receptors. The symptoms include mental state alterations (e.g., agitation, confusion), neuromuscular excitation (e.g., myoclonus, tremor), and autonomic dysregulation (e.g., hyperthermia, tachycardia). Similar symptoms can also be induced in rodents, especially in rats, whereas in冰雹 发表于 2025-3-22 21:12:10
5-HT4 Receptor Subtype, β-Arrestin Level, and Rapid-Onset Effects of Antidepressant Drugsspects of the disease. The use of exogenously administered corticosterone (CORT model) can mimic the effects of a chronic stress and has been validated as an animal model to study disease states displaying some hallmark characteristics of anxiety and depression observed in patients..Recently, we hav比喻好 发表于 2025-3-23 03:15:38
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