RACE 发表于 2025-3-23 13:34:27
Incorporation of Selenium into Bacterial Selenoproteins,um (1). Thus, . was the first organism for which a biological role of selenium was demonstrated. It took almost 40 years to identify the enzyme responsible for formate oxidation under the aerobic conditions used by Pinsent:It is formate dehydrogenase 0 (FDH.), which presumably is a respiratory chainmitral-valve 发表于 2025-3-23 15:21:52
Selenocysteine tRNASec Isoacceptors as Central Components in Selenoprotein Biosynthesis in Eukgnals the translational insertion of selenocysteine into protein. These studies include the demonstration that (1) a TGA codon (that corresponds to a selenocysteine moiety in the resulting gene products ) occurs in the open reading frame of genes for formate等待 发表于 2025-3-23 18:23:31
,Intracellular Glutathione Peroxidases — Structure, Regulation, and Function, in the protection of erythrocytes against oxidative hemolysis. Similarly, John Rotruck, working in Professor Hoekstra’s laboratory, focused on GPX in his search for an enzymatic function that made selenium (Se) an antioxidant (2). The unraveling of the Se/GPX story has fascinated a generation of scmanifestation 发表于 2025-3-24 01:02:47
Extracellular Glutathione Peroxidase:A Distinct Selenoprotein, to the diet (1 – 7). In patients undergoing chronic parenteral nutrition, selenium deficiency has been associated with heart failure (5–7) muscle pain (8) and muscle weakness (9). A role for selenium in intracellular metabolism of mammals was first realized in 1973 with the discovery that selenium性满足 发表于 2025-3-24 06:11:58
,Roles of Selenium in Type I Iodothyronine 5’-Deiodinase and in Thyroid Hormone and Iodine Metabolisats that were also vitamin E—deficient (1). Subsequently, selenium deficiency was shown to cause several diseases in other animals, usually associated with concurrent vitamin E deficiency (2). Although some conditions that responded to selenium or vitamin E supplementation were thought to be caused羊齿 发表于 2025-3-24 08:11:02
http://reply.papertrans.cn/87/8644/864363/864363_16.pngrheumatology 发表于 2025-3-24 12:54:02
,The Mitochondrial Capsule Selenoprotein—A Structural Protein in the Mitochondrial Capsule of Mammalpecialized structure associated with the outer mitochondrial membrane of spermatozoa in mammals. For example, intraperitoneal injections of .Se and autoradiography demonstrate that .Se is primarily incorporated into the midpiece of spermatozoa, the segment of the sperm tail containing the mitochondrCAGE 发表于 2025-3-24 17:42:41
http://reply.papertrans.cn/87/8644/864363/864363_18.pngJudicious 发表于 2025-3-24 19:31:09
http://reply.papertrans.cn/87/8644/864363/864363_19.png金桌活画面 发表于 2025-3-25 02:58:11
Keshan Disease and Selenium Status of Populations in China,1935 (Apei, 1937), the disease has also been recognized in many other locations. An inscription on a stone pillar in Huanglong County of Shaanxi Province suggests that Keshan disease occurred there in 1812 and thus is not a new condition (Shan and Xue, 1987). Keshan disease has been a serious public