不能根除 发表于 2025-3-26 23:20:51
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http://reply.papertrans.cn/84/8311/831051/831051_32.pnghidebound 发表于 2025-3-27 07:56:56
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Eui-Taek Jeong,Sang-Don Lee,Kyung-Mi Na,Chang-Hun Leeation of MPTP toxicity. This also applies for misfolded proteins such as alpha synuclein. Again, multiple brain areas as well as peripheral sites are increasingly recognized to be affected both during MPTP toxicity and sporadic PD patients. Nowadays it seems that MPTP per se did not lead to discovermanifestation 发表于 2025-3-27 14:45:00
http://reply.papertrans.cn/84/8311/831051/831051_35.pngBravado 发表于 2025-3-27 18:40:07
Hironobu Wakabayashi,Yutaka Hiroi,Kenzaburo Miyawaki,Akinori Ito nerve cells. An example is the dinoflagellate toxin okadaic acid, an inhibitor of certain serine-threonine protein phosphatases, enzymes that occur widely in different cell types in animals and plants as well as microorganisms .. In fact, an okadaic acid sensitive form of this enzyme has been isola舰旗 发表于 2025-3-27 22:10:23
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Seung-Keol Ryu,Byeong-Min Jeong,Han-Lim Chois and ion-channel function, enzyme catalysis, and metal-mediated generation of free radicals .. Little information exists on the effects of heavy metals on proteins that contain structural repeats that are stabilized and coordinated by metal cations such as Zn. While the majority of such proteins ar锡箔纸 发表于 2025-3-28 09:23:54
Min-Gyu Kim,Hyun-Bin Kim,Hae-Won Parkrs such as a prolonged course of development, immaturity of the blood-brain barrier (BBB), and lack of regeneration of damaged CNS neurons. One of the more insidious aspects of developmental neurotoxicity is that its functional manifestations may not be readily apparent at birth or in infancy, but rspinal-stenosis 发表于 2025-3-28 13:18:10
Myeongwoo Jeong,Junho Choi,Hyun Myungr EPA regulatory jurisdiction. The considerable scientific literature available regarding investigation of the potential developmental neurotoxicity of pharmaceuticals and drugs of abuse . will also be discussed. However, by focusing on studies performed in general agreement with regulatory guidelin