Capitulate
发表于 2025-3-30 10:04:07
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孤僻
发表于 2025-3-30 15:59:30
Puja Karmakar,Suchismita Pal,Monalisa Mishrato hypoxia impact the metabolic phenotype of cancer cells. Such adaptations include increased glucose uptake, increased lactate production, and increased levels of other metabolites that stabilize HIF-1α, leading to a vicious circle of hypoxia-induced tumor growth.
预定
发表于 2025-3-30 17:39:55
Amalesh Bera,Tapas Kumar Dutta,Manojit Bhattacharya,Bidhan Chandra Patra,Utpal Kumar Sarls and characteristics based on varying the copy number of HREs in response to cellular hypoxia. We explain how to clone HREs into luciferase reporter constructs in the sense, antisense, and dual directions to measure luciferase expression for functional analyses.
拥护者
发表于 2025-3-31 00:23:18
Ajaya Kumar Rout,Sangita Dixit,Sujata Dey,Pranaya Kumar Parida,Manojit Bhattacharya,Sukanta Kumar Prevaluated in two-dimensional (2D) and 3D cultivation platforms during exposure to hypoxia (1% O.) and normoxia (21% O.) using fluorescence microscopy and flow cytometry. We show that hypoxia reporter MSCs exhibit a hypoxia-induced fluorescence signal in both 2D and 3D cultivation platforms with fast
Microaneurysm
发表于 2025-3-31 02:45:36
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拾落穗
发表于 2025-3-31 06:55:18
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overbearing
发表于 2025-3-31 12:14:06
Jasmin Rout,Gunanidhi Sahoo of VHL results in constitutive activation of HIF and a pseudo-hypoxic phenotype. Here, we review efforts to target either VHL or the hypoxic phenotype to identify pathways and agents as potential cancer therapeutics. Particular focus is given to distinguish between HIF-dependent and HIF-independent