reaching 发表于 2025-3-23 11:04:58
The need for disease-modifying drugsre potentially toxic. Studies to date have indicated that only a small percentage of patients starting treatment with disease-modifying drugs may derive long-term benefit. A high percentage of patients drop out because of adverse reactions. When analysed in terms of cost versus benefit these treatments may be neither effective nor efficient.Creditee 发表于 2025-3-23 14:41:38
Gold in the treatment of rheumatoid arthritise achieved at a high price in terms of toxicity; even when long-term treatment is attempted, only a minority of patients will remain on treatment after three years. The place of gold salts in the treatment of rheumatoid arthritis needs to be reassessed.天文台 发表于 2025-3-23 19:17:55
The need for disease-modifying drugsThis is because there is difficulty in determining which parameters accurately reflect disease activity and disease progression. The Stanford health assessment questionnaire, together with newer radiological techniques, may provide the means by which these assessments can be made..These treatments aineffectual 发表于 2025-3-23 23:02:23
Gold in the treatment of rheumatoid arthritis reduce symptoms and signs of synovitis and improve patient well-being to a greater extent than placebo. This advantage will persist for one year after injections have been stopped, but can no longer be demonstrated after a further year. There is no compelling evidence that treatment for longer thanMundane 发表于 2025-3-24 03:36:49
http://reply.papertrans.cn/84/8301/830096/830096_15.png绝种 发表于 2025-3-24 08:08:33
http://reply.papertrans.cn/84/8301/830096/830096_16.pngpancreas 发表于 2025-3-24 12:19:18
Immunosuppressive therapy for rheumatoid arthritisophosphamide and chlorambucil (alkylating agents), azathioprine (purine analogue) and methotrexate (folic acid analogue). A Medline search and review articles were used to identify clinical trials of these drugs in patients with rheumatoid arthritis. A scoring system was used to assess the design a流浪 发表于 2025-3-24 17:37:55
http://reply.papertrans.cn/84/8301/830096/830096_18.pnggiggle 发表于 2025-3-24 20:13:59
Conclusionspants, one and all, prescribe one or more of these agents almost every working day of their lives, yet the use of these drugs remains highly controversial. How they should be used — indeed, whether some of them should be prescribed at all — and what studies we should be planning to answer these quesgenuine 发表于 2025-3-24 23:28:43
Macmillan Publishers Limited 1984