首创精神
发表于 2025-3-26 21:41:07
AMD-Associated HTRA1 Variants Do Not Influence TGF-β Signaling in Microgliaotypes. Here, we show that an HtrA1 isoform carrying AMD-associated SNPs in exon 1 exhibits increased proteolytic activity. However, when incubating TGF-β-treated reactive microglia with HtrA1 protein variants, neither the wildtype nor the SNP-associated isoforms changed microglia activation in vitro.
Pastry
发表于 2025-3-27 04:41:10
A Review of Pathogenic Drivers of Age-Related Macular Degeneration, Beyond Complement, with a Focus ppreciate the different known morphological endpoints associated with the various pathogenic pathways, in order to derive further insights, for the ultimate purpose of disease modeling and development of effective therapeutic interventions.
新字
发表于 2025-3-27 06:45:48
Melatonin as the Possible Link Between Age-Related Retinal Degeneration and the Disrupted Circadian e a major factor contributing to the impaired balance between phagocytosis and clearance and increased levels of reactive oxygen species resulting in degenerative changes in the retina. This minireview summarizes studies linking AMD with melatonin production and discusses challenges and perspectives of this area of research.
我不怕牺牲
发表于 2025-3-27 10:51:13
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conjunctiva
发表于 2025-3-27 14:38:32
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独轮车
发表于 2025-3-27 20:02:47
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思乡病
发表于 2025-3-28 00:34:33
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我不死扛
发表于 2025-3-28 05:51:09
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同义联想法
发表于 2025-3-28 10:04:57
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使服水土
发表于 2025-3-28 13:04:41
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