PTCA635 发表于 2025-3-26 21:30:31
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Resistance Mechanisms to Cyclin-Dependent Kinase Inhibitors, cycle deregulation is a hallmark of cancer, and CDKs have long been considered attractive targets for anti-cancer agents. After initial failures of pan-CDKi in clinical trials, two highly specific CDK4/6 inhibitors, palbociclib and ribociclib, are now FDA-approved in hormone receptor-positive breasarboretum 发表于 2025-3-27 07:27:20
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Mechanisms of Action and Resistance of Trastuzumab in Breast Cancer,wever, resistance to trastuzumab, either . or acquired resistance, presents a major clinical challenge. Here, we summarize the mechanisms of action and resistance of trastuzumab in breast cancer and discuss potential strategies to overcome resistance.Temporal-Lobe 发表于 2025-3-27 20:57:56
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a geometric structure or a long-range interaction. The farther spin interactions than the nearest sites stem from a coupling with other degrees of freedom in many realistic materials. Among them, the spin-lattice interaction has a large contribution for the effective spin interaction, and the spin-P娴熟 发表于 2025-3-28 03:36:23
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http://reply.papertrans.cn/83/8285/828448/828448_39.pngSubstance 发表于 2025-3-28 12:54:49
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