载货清单
发表于 2025-3-23 13:25:49
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RACE
发表于 2025-3-23 15:41:14
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ANT
发表于 2025-3-23 21:55:26
,Sequential Optimal Experimental Design of Perturbation Screens Guided by Multi-modal Priors,nference of gene circuits, the discovery of therapeutic targets and the reprogramming and engineering of cells. In recent years, Perturb-seq, pooled genetic screens with single cell RNA-seq (scRNA-seq) readouts, has emerged as a common method to collect such data. Despite technological advancements,
goodwill
发表于 2025-3-23 22:39:50
,Efficient Analysis of Annotation Colocalization Accounting for Genomic Contexts,fications. A common task is to compare two annotations to determine if one is enriched or depleted in the regions covered by the other. We study the problem of assigning statistical significance to such a comparison based on a null model representing two random unrelated annotations. To incorporate
visual-cortex
发表于 2025-3-24 05:47:57
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合并
发表于 2025-3-24 08:43:59
,FragXsiteDTI: Revealing Responsible Segments in Drug-Target Interaction with Transformer-Driven Intmance. We propose a novel transformer-based model, FragXsiteDTI, that aims to address these challenges in DTI prediction. Notably, FragXsiteDTI is the first DTI model to simultaneously leverage drug molecule fragments and protein pockets. Our information-rich representations for both proteins and dr
过份好问
发表于 2025-3-24 11:32:01
,An Integer Programming Framework for Identifying Stable Components in Asynchronous Boolean Networks In particular, Boolean network models have been a prime research focus and dozens of manually curated Boolean models are available in public databases. A key challenge in studying the dynamics of these models is determining their asymptotic behavior, that is the state-sets or attractors they conver
PLIC
发表于 2025-3-24 17:08:07
ImputeCC Enhances Integrative Hi-C-Based Metagenomic Binning Through Constrained Random-Walk-Based tating the reconstruction of high-quality metagenome-assembled genomes (MAGs) from complex microbial communities. However, current Hi-C-based contig binning methods solely depend on Hi-C interactions between contigs to group them, ignoring invaluable biological information, including the presence of
野蛮
发表于 2025-3-24 22:35:11
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Suggestions
发表于 2025-3-25 02:14:13
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