抛媚眼 发表于 2025-4-1 04:28:25
Karl Mengere optimization methods. We define an optimal control problem to adjust parameters in single-cell models so that the trans-membrane potential predicted by a model fits in a least-square (LS) sense the potential recorded over time. To account for restitution properties, this LS function measures the dInterim 发表于 2025-4-1 07:31:03
Karl Mengerhronic AF patients, where targets for optimal ablation are unknown. Recent clinical evidence suggests an association of atrial fibrosis with locations of re-entrant drivers (RDs) sustaining AF. However, the knowledge of optimal ablation locations based on patient-specific fibrosis distribution is la