Condescending 发表于 2025-3-28 16:07:43
http://reply.papertrans.cn/83/8264/826308/826308_41.png吝啬性 发表于 2025-3-28 19:32:15
Relaxin is an important factor for uterine differentiation and implantation in the marmoset monkey birth canal and at least in some species a suppression of spontaneous contractions . Such findings are generally observed in animal models, like the rat and pig, which show a marked relaxin physiology with maximum relaxin levels during the last trimester of pregnancy. For primates, however, thDAUNT 发表于 2025-3-28 23:03:25
http://reply.papertrans.cn/83/8264/826308/826308_43.pngoblique 发表于 2025-3-29 06:32:05
http://reply.papertrans.cn/83/8264/826308/826308_44.pngpromote 发表于 2025-3-29 07:51:19
Intersection of the relaxin and estrogen signalling pathways in the uteruse uterus during pregnancy, remodelling of the reproductive tract in preparation for parturition, and development of the mammary glands . The mechanisms by which relaxin exerts these effects, however, remain unclear, in large part because the relaxin receptor has not yet been cloned. Interestingly某人 发表于 2025-3-29 14:18:50
Relaxin up-regulates rat uterine vascular endothelial growth factor mRNA ,reproductive tract prior to parturition . Most of these well-established effects of relaxin have been characterized with regard to relaxin’s systemic effects as a circulating factor released from the corpus luteum during pregnancy and prior to parturition . Many of relaxin’s acute effects, hBARGE 发表于 2025-3-29 19:00:53
Comparative aspects of relaxin and relaxin-like factor (Insulin 3) in the placental trophoblastng or fusing with the maternal mucosa. The dominating placenta of most mammals is the chorio-allantoic placenta. Both members of the relaxin family, relaxin itself and the structurally closely related relaxin-like factor (RLF) also known as INSL3 , are expressed at the fetomaternal interface o同步信息 发表于 2025-3-29 20:54:55
Secretion of matrix metalloproteinase-2, tissue inhibitor of metalloproteinase-1 and human chorionicydig insulin-like peptide (LEY I-L, RLF, INSL3) and peptides encoded by INSL4 (Early placenta insulin-like), INSL5 and INSL6 genes . Whereas the physiological role of relaxin has been well assessed in late pregnancy and parturition , recent studies in primates and humans have shown that re充满人 发表于 2025-3-30 03:37:33
Molecular remodelling of members of the relaxin family during primate evolutiongh sequence variability within and between taxonomic groups among land animals. Widely regarded as a hormone of the female reproductive tract, relaxin is expressed in the ovary and at the feto-maternal interface . Known as a marker of human postpubertal testicular Leydig cells in various speciesPresbycusis 发表于 2025-3-30 04:23:52
Ynes, California in 1981 and then the First International Congress on the Hormone Relaxin in Florence in 1982. After a hiatus of several years, the Second International Congress on the Hormone Relaxin was held in Adelaide in 1994. Since that time, the enormous advances in molecular biology and prot