flaunt 发表于 2025-3-25 06:44:56
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,Regulation of IFN-γ Expression,enetic control, such as chromosome access, DNA methylation, and histone acetylation. The more we learn about the control of this regulatory protein will allow us to apply this knowledge in the future to effectively manipulate IFN-. expression for the treatment of infections, cancer, inflammation, and autoimmune diseases.恶臭 发表于 2025-3-25 14:14:18
Regulation and Immune Function of IL-27,s diseases as well as cancers. In this chapter, the biological characters of IL-27 have been reviewed, including the molecular mechanisms of IL-27 production and the underlying cellular signaling pathway. The regulatory effects of IL-27 on immune responses in autoimmune disease, infectious disease, and cancer are also discussed.CLAM 发表于 2025-3-25 18:51:30
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The Interleukin-1 Family,r. IL-1β is one of the most prominent mediators of inflammation resulting in fever and immune activation via binding to IL-1 receptor 1. Due to its potency, its secretion is tightly regulated. First the transcription of the biologically inactive proform is induced by TLR activation, TNF, or IL-1 rec谄媚于性 发表于 2025-3-26 00:42:34
Regulation of IL-4 Expression in Immunity and Diseases,g of its cellular sources and function. In addition to T cells, IL-4 is produced by innate lymphocytes, such as NTK cells, and myeloid cells, such as basophils and mast cells. It is a signature cytokine of type 2 immune response but also has a nonimmune function. Its expression is tightly regulated新手 发表于 2025-3-26 06:45:06
Regulation of IL-6 in Immunity and Diseases,ries occur, IL-6 is promptly produced by monocytes and macrophages and contributes to removal of infectious agents and restoration of damaged tissues through activation of immune, hematological, and acute-phase responses. Once stress is removed from the host, IL-6 synthesis ends, but uncontrolled ex垄断 发表于 2025-3-26 12:19:58
Regulation of Interleukin-10 Expression,igens. Loss of IL-10 results in the spontaneous development of inflammatory bowel disease as a consequence of an excessive immune response to the gut microbiota. IL-10 also functions to prevent excessive inflammation during the course of infection. IL-10 can be produced in response to pro-inflammato考得 发表于 2025-3-26 14:26:35
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Regulation of Interleukin-17 Production,thogens confers host the ability to prevent, restrict, and eliminate microorganisms and further trigger adaptive immunity to provide extended eradication of the pathogens as well as long-term protection of the host from recurrent infections. During this process, various types of cytokines are requir