Ostrich 发表于 2025-3-26 23:49:22

The Lon AAA+ Proteaseent protein degradation was established through the findings that led to the discovery of Lon. Therefore, this chapter begins with a historical perspective, describing the milestones that led to the discovery of Lon and ATP-dependent proteolysis, starting from the early findings in the 1960s until t

血友病 发表于 2025-3-27 04:25:59

FtsH Protease-Mediated Regulation of Various Cellular Functionsred to the inner membrane. It plays crucial roles in a variety of cellular processes. It is responsible for the degradation of both membrane and cytoplasmic substrate proteins. Substrate proteins are unfolded and translocated through the central pore of the ATPase domain into the proteolytic chamber

Cytokines 发表于 2025-3-27 08:31:38

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Cacophonous 发表于 2025-3-27 12:02:30

Proteolytic Regulation of Stress Response Pathways in ,of protein homeostasis (proteostasis) in the cell, which is largely performed by a group of proteins, referred to as the protein quality control (PQC) network. This network of proteins, comprised of chaperones and proteases, is critical for maintaining proteostasis not only during favourable growth

使服水土 发表于 2025-3-27 17:18:03

Regulated Proteolysis: Control of the , σ,-Dependent Cell Envelope Stress Response. These conserved proteolytic pathways share a common design that involves the sequential proteolysis of a membrane-bound regulatory protein by two proteases. Proteolysis releases the regulator, which is inactive in its membrane-bound form, into the cytoplasm where it performs its cellular function.

玷污 发表于 2025-3-27 20:27:41

Bacterial Proteases and Virulenceserved Clp and Lon proteases that directly contribute to virulence through the timely degradation of virulence regulators and indirectly by providing tolerance to adverse conditions such as those experienced in the host. In the membrane, HtrA performs similar functions whereas the extracellular prot

没有贫穷 发表于 2025-3-27 22:37:44

Roles of Cdc48 in Regulated Protein Degradation in YeastCP) is a key regulator of intracellular proteolysis in eukaryotes. It uses the energy derived from ATP hydrolysis to segregate ubiquitylated proteins from stable assemblies with proteins, membranes and chromatin. Originally characterized as essential factor in proteasomal degradation pathways, Cdc48

Irritate 发表于 2025-3-28 04:46:03

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使声音降低 发表于 2025-3-28 09:58:50

The Pup-Proteasome System of ,Actinomycetales. . (.), an Actinomycete pathogenic to humans, requires proteasome function to cause disease. In this chapter, we describe what is currently understood about the biochemistry of the . proteasome and its role in virulence. The characterization of the . proteasome has led to the discove

固定某物 发表于 2025-3-28 13:42:30

Archaeal Proteasomes and Sampylationroteasome system (UPS) of eukaryotes. Archaeal proteasomes have served as excellent models for understanding how proteins are degraded by the central energy-dependent proteolytic machine of eukaryotes, the 26S proteasome. While sampylation has only recently been discovered, it is thought to be linke
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查看完整版本: Titlebook: Regulated Proteolysis in Microorganisms; David A. Dougan Book 2013 Springer Science+Business Media Dordrecht 2013 AAA+ superfamily.adaptor