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ts and myofibroblasts and extensive deposition of extracellular matrix (ECM) proteins. The microenvironment of the fibrotic ECM is characterized by altered biomechanical (stiffness) as well as altered biochemical (growth factors) properties. The ECM can also affect the behavior of multiple lung cell柏树 发表于 2025-3-25 12:34:35
Shuvro Prosun Sarkerathogenesis believed to include vascular abnormalities with accompanying autoimmunity leading to tissue sclerosis. This chapter summarizes the current knowledge about systemic sclerosis pathogenesis and reviews the role of immune imbalance and its relationship with vascular damage and sustained scle令人苦恼 发表于 2025-3-25 16:35:59
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Shuvro Prosun Sarker therapeutic effects. However, thus far there are no effective clinical treatments to specifically block fibrotic processes, underscoring the necessity of enhanced research efforts in this arena. The hallmark of vascular fibrotic disorders is extensive extracellular matrix remodeling primarily mediaiodides 发表于 2025-3-26 07:45:02
Shuvro Prosun Sarker current and future drug therapies.This book provides a comprehensive account of the pathogenesis and treatment of intestinal fibrosis, covering both the clinical and molecular aspects of the disease. It begins by describing the epidemiology and genetics of fibrostenosing IBD in Crohn’s disease and演绎 发表于 2025-3-26 10:46:39
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Shuvro Prosun Sarkeresults have shown that the oligomeric and fibrillar aggregates of the amyloid β-peptide (Aβ) play a critical role in the pathogenesis of Alzheimer’s disease (AD). Therefore, the accessibility of certain amounts of pure Aβ peptide is necessary for the studies of the mechanism of neurotoxicity. In thiPerennial长期的 发表于 2025-3-26 20:36:05
Shuvro Prosun Sarkeresults have shown that the oligomeric and fibrillar aggregates of the amyloid β-peptide (Aβ) play a critical role in the pathogenesis of Alzheimer’s disease (AD). Therefore, the accessibility of certain amounts of pure Aβ peptide is necessary for the studies of the mechanism of neurotoxicity. In thi