UNT 发表于 2025-3-23 10:16:31
Strategies to Develop Therapeutic N- and O-Hyperglycosylated Proteins involves the initial stage of designing N- and/or O-hyperglycosylated muteins to be expressed by mammalian cells and includes the upstream and downstream processing stages necessary to develop hyperglycosylated versions of the proteins of interest with the purpose of beginning the long road toward producing biobetters.泥沼 发表于 2025-3-23 13:51:26
http://reply.papertrans.cn/83/8241/824093/824093_12.png极少 发表于 2025-3-23 21:44:19
Microplate-Based Method for High-Throughput Screening (HTS) of Chromatographic Conditions Studies foimic chromatographic purification steps was established, several studies were performed successfully including scale down purification. Here, we propose a method for studying different purification conditions that can be used for any recombinant protein, including complex and glycosylated proteins, using low binding filter microplates.FLIC 发表于 2025-3-24 00:19:09
Platforms for Recombinant Therapeutic Glycoprotein Production,es, with numerous products currently approved for clinical use. The choice of the expression system is a key step toward a successful functional protein production, since glycosylation influences yield, pharmacokinetics, biological activity, and immunogenicity. This chapter covers the general aspectgentle 发表于 2025-3-24 03:24:57
Uncovering Innovation Features and Emerging Technologies in Molecular Biology through Patent Analyshnology for the development of their research, such as biotechnology, need to be aware of the frontier state-of-the-art technology and the knowledge incrusted within it. Although the information available in scientific articles is well explored in academic environment, the patent literature, where mGEM 发表于 2025-3-24 07:25:35
http://reply.papertrans.cn/83/8241/824093/824093_16.pngLocale 发表于 2025-3-24 10:51:43
http://reply.papertrans.cn/83/8241/824093/824093_17.pngduplicate 发表于 2025-3-24 16:53:18
Production of Recombinant Factor VIII in Human Cell Linesential immunogenic reactions. Recombinant proteins produced in nonhuman cells can have in its structure glycan epitopes, such as Galα1,3-Gal (alpha-Gal) and N-glycolylneuraminic acid (Neu5Gc) residues, that are antigenic to humans and can potentially affect the efficacy of the recombinant product. TConfess 发表于 2025-3-24 20:44:14
http://reply.papertrans.cn/83/8241/824093/824093_19.png异常 发表于 2025-3-25 00:16:43
Production of Recombinant Rabies Virus Glycoprotein by Insect Cells in a Single-Use Fixed-Bed Bioreafor harvesting a membrane-associated viral glycoprotein with high quality in terms of preserved protein structure and biological function. Here, we describe the procedures for establishing genetically modified . Schneider 2 (S2) cell cultures in the iCELLis nano bioreactor and for quantifying by ELI