惰性气体 发表于 2025-3-23 12:06:57

Hans Peter Killguss,Jan Schedlerfor myofiber integrity. Exon skipping therapy is an emerging strategy for restoring the open reading frame of the . gene to produce functional protein in DMD patients by skipping single or multiple exons. Although antisense oligonucleotides are able to target pre-mRNA for exon skipping, their half-l

并排上下 发表于 2025-3-23 14:32:34

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Additive 发表于 2025-3-23 19:54:22

Alexander Häuslereteplirsen) and Spinraza (nusinersen) for the treatment of patients with Duchenne muscular dystrophy (DMD) and spinal muscular atrophy (SMA) was the most noteworthy accomplishment in 2016. Exon skipping uses short DNA-like molecules called antisense oligonucleotides (AONs) to correct the disrupted r

漂浮 发表于 2025-3-24 01:07:54

Michael Kiefer da sich frei schwebende Teilchen und Gase, die Überreste der ersten Generationen von Sternen nach dem Urknall, die in gewaltigen Supernovae explodierten, im Weltall im Laufe von Jahrmillionen zu einer Wolke verdichtet haben und diese schließlich durch ihre eigene Schwerkraft kollabierte. Hieraus bi

灵敏 发表于 2025-3-24 05:26:40

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CAJ 发表于 2025-3-24 09:52:57

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BUCK 发表于 2025-3-24 12:44:04

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Vasodilation 发表于 2025-3-24 16:25:55

Tomas Sager,Jürgen Peterstiated myoblasts. Herein, we describe an optimized methodology to prepare myoblasts differentiated from iPS cells by mRNA transfection of the CRISPR-Cas9 system to skip exon 45 in myoblasts, and evaluate the restored dystrophin by RT-PCR and Western blotting.

Rinne-Test 发表于 2025-3-24 21:58:15

Hans Peter Killguss,Jan Schedlertiated myoblasts. Herein, we describe an optimized methodology to prepare myoblasts differentiated from iPS cells by mRNA transfection of the CRISPR-Cas9 system to skip exon 45 in myoblasts, and evaluate the restored dystrophin by RT-PCR and Western blotting.

Cupidity 发表于 2025-3-25 00:48:45

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