不溶解 发表于 2025-3-23 12:11:58
http://reply.papertrans.cn/83/8234/823395/823395_11.pngspondylosis 发表于 2025-3-23 17:34:25
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le was developed after the observation that kainic acid induced striatal lesions which mimic many of the neuropathologic features of HD. We and others subsequently showed that quinolinic acid lesions, which spare NADPH-diaphorase neurons, produced an improved excitotoxic model. There however is no econsolidate 发表于 2025-3-23 22:55:28
http://reply.papertrans.cn/83/8234/823395/823395_14.pngSad570 发表于 2025-3-24 05:59:37
Ilya Gavrikov,Andrey V. Savchenkoneuroprotective drugs and the advent of potent and centrally available subtype-selective ligands has lead to an extensive investigation of the role of individual mGlu receptor subtypes in neurodegeneration. Pharmacological blockade of mGlu1 or -5 receptors or pharmacological activation of mGlu2/3 orCAMEO 发表于 2025-3-24 09:50:39
Alexey Mikhaylichenko,Yana Demyanenkormationally restricted analogue of L-glutamate, it was a potent agonist at glutamate receptors (Olney et al., 1974; Coyle and Schwarcz, 1976). Since the first reports of the perikaryal-specific neurotoxic action of intracerebrally injected KA, it has become increasingly apparent that the mechanism oTERRA 发表于 2025-3-24 13:56:43
Ivan Goncharov,Alexey Mikhaylichenko,Anatoly Kleschenkovrmationally restricted analogue of L-glutamate, it was a potent agonist at glutamate receptors (Olney et al., 1974; Coyle and Schwarcz, 1976). Since the first reports of the perikaryal-specific neurotoxic action of intracerebrally injected KA, it has become increasingly apparent that the mechanism oOratory 发表于 2025-3-24 17:03:47
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http://reply.papertrans.cn/83/8234/823395/823395_19.pngLeaven 发表于 2025-3-25 01:12:30
larize and excite neurones of the mammalian spinal cord (Curtis, .., 1959; 1960), and that similar excitatory effects could be elicited by a variety of other compounds chemically related to the natural substances (Curtis and Watkins, 1960; 1963). Curtis and Watkins (1960) set forth the criteria whic