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AT1-Receptors and Cellular Actions of Angiotensin II in Neuronal Cultures of Stroke Prone-Spontaneo-prone spontaneously hypertensive (SP-SH) rat brains. Bmax for AT.-receptor binding is 2-fold higher and is associated with a parallel increase in the levels of AT. preceptor mRNA in SP-SH rat brain neurons compared with WKY rat brain neurons. Ang II causes stimulation of both c-fos and norepinephriSIT 发表于 2025-3-26 05:43:28
Antisense Oligonucleotides for , Studies of Angiotensin Receptors,r translation. We have been using AS oligos to lower blood pressure by inhibiting angiotensin receptors and angiotensinogen in freely moving, whole animals. This recent application of antisense technology to . studies, opens a new way of approaching physiological problems with the precision of molecCRANK 发表于 2025-3-26 08:27:49
Interactions of Angiotensin II with Central Dopamine,omic nervous systems. Ang II also acts in the brain to augment its peripheral actions by stimulating salt appetite and drinking, elevating blood pressure, and by modulating the release of pituitary hormones. Blood borne Ang II can access the brain via the circumventricular organs which have a permeaCalibrate 发表于 2025-3-26 16:07:24
Regulation of the Hypothalmic-Pituitary-Adrenal Axis and Vasopressin Secretion,of pituitary hormones such as ACTH, prolactin and gonadotropins (1,2). With respect to ACTH, several in vitro studies in rodents and primates have shown that ANG II directly stimulates ACTH secretion and potentiates the stimulatory effect of corticotropin releasing hormone (CRH) through ANG II recep微生物 发表于 2025-3-26 19:03:29
Relationship Between the Drinking Response to Angiotensin II and Induction of Fos in the Brain, Either peripheral or central administration of Ang II induces water intake in water-replete animals. The dipsogenic effect of peripheral Ang II is abolished by either lesions of, or Ang II receptor antagonism in, the subfornical organ (SFO). The SFO is a circumventricular organ, and the fenestratio