Pepsin
发表于 2025-3-25 04:44:39
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overhaul
发表于 2025-3-25 08:35:41
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atopic-rhinitis
发表于 2025-3-25 15:22:21
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健壮
发表于 2025-3-25 16:47:00
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plasma-cells
发表于 2025-3-25 20:28:41
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Bereavement
发表于 2025-3-26 03:11:48
Prenylation of RabGTPases, Their Delivery to Membranes, and Rab Recyclinge able to interact with membranes. Here, we review the basic mechanism of geranlygeranylation and then address the still unsolved question of how prenylated Rabs are delivered to specific membranes. The evidence reviewed leads to a model in which specifically localized guanine nucleotide exchange fa
Expurgate
发表于 2025-3-26 05:06:45
Rab Proteins and the Organization of Organelle Membrane Domainsins consist of a cluster of specific lipids and proteins that provide membranes with a distinct molecular identity. Rab GTPases are one of the main coordinators of membrane domain formation and dynamics. In this chapter, we will give a brief introduction into Rab GTPases and focus on how they create
Optimum
发表于 2025-3-26 10:26:27
Effectors of Rab GTPases: Rab Binding Specificity and Their Role in Coordination of Rab Function and via a similar Rab surface area which shows the largest conformational changes upon nucleotide exchange. This surface is also involved in the interaction with other Rab interacting proteins. In spite of the high structural similarity of the Rab proteins, the Rab binding domains of effector proteins
NAVEN
发表于 2025-3-26 15:32:06
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Humble
发表于 2025-3-26 17:06:49
Rab GEFs and GAPs: The Enigma Variations polarisation and autophagy. Rabs undergo a cycle of activation involving GTP binding and inactivation involving GTP hydrolysis in response to cellular regulators. Each Rab has a cognate GDP–GTP exchange factor (GEF) promoting release of GDP and subsequent binding of GTP, and a GTPase activating pro