宗派 发表于 2025-3-21 17:41:33
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Tuning the Expression of Long Noncoding RNA Loci with CRISPR Interference,CRISPRi has negligible off-target effects and does not involve changes in the underlying genomic DNA sequence, it represents a valuable addition to the existing armamentarium used to investigate lncRNA biology.Overthrow 发表于 2025-3-22 12:40:53
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Tuning the Expression of Long Noncoding RNA Loci with CRISPR Interference,an genome, but only a subset has been involved in regulation of key cellular processes, organismal development, and diseases. Hence, the functional role for the majority of the lncRNA genes remains unknown. With the recent developments of different CRISPR/Cas9 technologies, the function of lncRNAs c