松软无力
发表于 2025-3-25 03:50:19
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Vertical
发表于 2025-3-25 11:00:28
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媒介
发表于 2025-3-25 13:44:30
Probing RNA Helicase Conformational Changes by Single-Molecule FRET Microscopy,lecules in solution, revealing the population of different conformational states present. With TIRF microscopy, surface-immobilized molecules can be imaged as a function of time, revealing sequences of conformational states and the kinetics of conformational changes.
Allowance
发表于 2025-3-25 16:58:12
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SLUMP
发表于 2025-3-25 23:37:58
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figure
发表于 2025-3-26 01:15:29
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石墨
发表于 2025-3-26 07:45:51
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图表证明
发表于 2025-3-26 09:47:59
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MOAN
发表于 2025-3-26 14:28:37
Identifying RNA Helicase Inhibitors Using Duplex Unwinding Assays,-throughput modalities. These optimized assays have enabled the application of rapid screening approaches to be applied toward discovering helicase inhibitors. This chapter provides detailed protocols for utilizing a medium to high-throughput approach for inhibitor discovery.
Concerto
发表于 2025-3-26 20:47:04
SRCD and FTIR Spectroscopies to Monitor Protein-Induced Nucleic Acid Remodeling,ynchrotron radiation circular dichroism (SRCD) and FTIR to analyze how proteins may change RNA structure. These include the analysis of RNA melting, or stabilization, of change in helical parameters and base stacking. The effects on the structure of RNA remodeling proteins are also presented.