burnish
发表于 2025-3-23 10:09:04
siRNA Library Screening to Identify Complementary Therapeutic Pairs in Triple-Negative Breast Canceon of the plasticity of such networks is stimulating the development of combinational therapy to overcome the limitations of one-dimensional therapies. Synergistic pairs of siRNAs or siRNA and drug combinations are the new frontiers in identifying effective therapeutic combinations. To elucidate eff
deviate
发表于 2025-3-23 14:43:30
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只有
发表于 2025-3-23 18:43:15
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insightful
发表于 2025-3-24 00:59:37
Relative Quantification of siRNA Strand Loading into Ago2 for Design of Highly Active siRNAs,ay proteins, including Argonaute 2 (Ago2). Based on these interactions, one strand of the siRNA is loaded into Ago2 forming the active RNA-induced silencing complex (RISC). Optimal siRNAs maximize RISC activity against the intended target and minimize off-target silencing. To achieve the desired act
植物学
发表于 2025-3-24 05:03:24
VEGFA Gene Silencing in CXCR4-Expressing Cells via siRNA Delivery by Means of Targeted Peptide Carrers. The efficacious delivery of therapeutic siRNAs into the cells is a crucial step in RNA interference (RNAi) application, but it remains challenging. Non-viral vectors can provide specific cellular uptake, stable siRNA complex formation, and intracellular siRNA release. Recently, we evaluated mod
CRAMP
发表于 2025-3-24 08:31:10
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fallible
发表于 2025-3-24 12:21:04
Combinatorial siRNA Polyplexes for Receptor Targeting,parkled intense investigations. To develop tumor-specific carriers for cytosolic and systemic siRNA delivery, our laboratory has recently generated folate-conjugated targeted combinatorial siRNA polyplexes based on sequence-defined oligomer platform compatible with solid-phase-supported synthesis. T
irradicable
发表于 2025-3-24 15:08:00
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flavonoids
发表于 2025-3-24 20:59:36
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Largess
发表于 2025-3-24 23:48:25
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