Dna262
发表于 2025-3-28 16:17:17
Additional Topics,ata. We also extend the concept of study success to regulatory and technical success. We wrap up the book by sharing the story of dabigatran where a higher dose of the drug, and not a lower dose, was approved based on an overall benefit–risk assessment.
LAVE
发表于 2025-3-28 20:22:34
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habitat
发表于 2025-3-29 01:32:52
A Frequentist Decision-Making Framework,velopment, the two actions correspond to progressing or not progressing a drug for further development. These two actions are fundamental to decision making in drug development. The Frequentist approach to statistical inference involves examining probability via its long-run frequency interpretation
CURL
发表于 2025-3-29 03:19:35
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FEMUR
发表于 2025-3-29 09:57:51
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哭得清醒了
发表于 2025-3-29 11:59:53
Incorporating Information from Completed Trials and Other Sources in Future Trial Planning,consider the Bayesian approach to incorporate existing information into future trial planning. Under the Bayesian approach, prior distributions are used to describe the accumulated knowledge about unknown parameters such as responses to controls in previous trials and estimates pertaining to treatme
博识
发表于 2025-3-29 16:04:43
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Compassionate
发表于 2025-3-29 22:55:39
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帐单
发表于 2025-3-30 02:13:47
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愚笨
发表于 2025-3-30 07:11:00
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