珐琅 发表于 2025-3-26 23:26:32
Oxidation-Sensitive Transcription and Gene Expression in Atherosclerosis pulmonary emphysema, neurodegenerative disorders and atherosclerosis has focused on the putative role of ROS as cellular damaging agents through the potential toxic oxidative modification of macromolecules such as proteins, lipids and DNA and on the cytotoxicity of free radicals and their reactionBORE 发表于 2025-3-27 03:46:26
Atherosclerosis, Oxidative Stress, and Endothelial Functiontes alone, 5.8 million patients are discharged from the hospital annually with a diagnosis of cardiovascular disease (CVD) and in 1995 CVD claimed over 960,000 lives (1). This represents approximately 41% of all deaths in the United States and places cardiovascular disease as the number one cause of有毒 发表于 2025-3-27 08:05:52
Oxidants and Antioxidants in Platelet Functionrecise mechanisms that underlie these observations, however, are not clear. While the beneficial effects of antioxidants have been attributed to the prevention of oxidative modification of low-density lipoprotein (LDL) and the inhibition of atherogenesis, other factors may also be important. PlateleAdherent 发表于 2025-3-27 13:25:02
Antioxidants and Atherosclerosis: Animal Studiesd world, claiming over 960,000 lives annually in the United States alone (1). A wealth of data now links serum cholesterol, in particular low-density lipoprotein (LDL) cholesterol (2) to the development of atherosclerosis. Despite this causative association between LDL cholesterol and atherosclerosiPolydipsia 发表于 2025-3-27 14:32:19
Human Studies of Antioxidants and Vascular Functiont suggest an association between increased intake of certain antioxidant vitamins and reduced risk for CVD. It is important to realize, however, that the putative mechanisms of any benefit remain uncertain. Investigations in animal models indicate that increased oxidative stress contributes to the aglomeruli 发表于 2025-3-27 21:47:55
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Glycation and Glycoxidation in Diabetic Vascular Diseasee body (type I, insulin dependent diabetes mellitus (IDDM)) and when there is an excess of circulating insulin (type II, non-insulin dependent diabetes mellitus (NIDDM)). Type I diabetes is generally associated with a young or juvenile onset, while Type II diabetes typically occurs with older age an闲荡 发表于 2025-3-28 02:19:56
Advanced Glycosylation Endproducts and Diabetic Vascular Diseaseretinopathy, nephropathy, neuropathy, and atherosclerotic vascular disease (1). Since diabetes mellitus afflicts at least 12 million individuals in the United States alone, the contribution of these complications to the overall morbidity and mortality of this disease is considerable (1,2). An import出汗 发表于 2025-3-28 09:14:28
Hyperglycemia and Diabetes — Induced Vascular Dysfunction: Role of Oxidative Stress lipid peroxides (., malondialdehyde) in plasma of experimental diabetic rodents (1–3) and in plasma of human type I and type II diabetes mellitus (2,4-7). More recently, F.-isoprostanes, nonenzymatic peroxidation products, were shown to be increased in plasma of diabetic patients (8). In addition tANT 发表于 2025-3-28 12:25:16
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