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Directed Differentiation of Mouse Embryonic Stem Cells Into Inner Ear Sensory Epithelia in 3D Cultuthree-dimensional (3D) culture system that efficiently generates inner ear sensory epithelia from aggregates of mouse embryonic stem (mES) cells. By mimicking the activations and repressions of key signaling pathways during in vivo inner ear development, mES cell aggregates are sequentially treatedadmission 发表于 2025-3-26 01:19:09
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Functional Hair Follicle Regeneration by the Rearrangement of Stem Cells,organogenesis during adulthood. Previously, we demonstrated that bioengineered hair follicle germs could regenerate functional hair follicles via a three-dimensional cell manipulation technique, which we named the “organ germ method.” We could also regulate the type of hair follicle and pigmentationCAPE 发表于 2025-3-26 13:48:36
Functional Salivary Gland Regeneration,ion, cleaning, and swallowing. Salivary gland dysfunction causes dry mouth syndrome, which includes many oral problems, such as dental caries, bacterial infection, mastication dysfunction, and swallowing dysfunction. Therefore, salivary gland regeneration is expected, and we attempted to establish abadinage 发表于 2025-3-26 20:44:47
Generation of a Bioengineered Lacrimal Gland by Using the Organ Germ Method,yonic ocular surface epithelium through reciprocal epithelial and mesenchymal interaction, which is organized by interactive regulation of various pathways of signaling molecules. Current development of an in vitro three-dimensional cell manipulation procedure to generate a bioengineered organ germ,