PLAYS 发表于 2025-3-23 13:12:06

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dithiolethione 发表于 2025-3-23 15:48:12

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收集 发表于 2025-3-23 18:46:00

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homocysteine 发表于 2025-3-23 23:24:54

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morale 发表于 2025-3-24 05:08:14

3C-Like Protease (3CLpro),ntiviral drugs. This chapter firstly did the work skillfully by locally optimizing the structures of SARS-CoV-2 3C-like protease (3CLpro) in complex with its inhibitor, N3/carmofur (6LU7.pdb & 7BQY.pdb/7BUY.pdb), from COVID-19 virus; then some new structural bioinformatics from the structures optimi

高度表 发表于 2025-3-24 09:14:11

RNA-Dependent RNA Polymerase (RdRp),tors, i.e., NSP7 and NSP8 (6M71.pdb and 7BTF.pdb), respectively, from COVID-19 virus; then some new structural bioinformatics from the structures optimized for developing therapies of the currently fatal COVID-19 virus are reported. Currently, lots of researchers are using optimization to screen, do

事情 发表于 2025-3-24 11:01:18

RNA Helicase,too. It facilitates/stimulates SARS-CoV-2 RdRp backtracking. Molecular dynamics (MD) simulations of the NSP13.-BTC. and NSP13.-BTC. complexes were done in Malone et al. (Proc Natl Acad Sci USA 118(19):e2102516118, 2021) and confirmed the results: “the single-stranded 3’-segment of the product-RNA ge

权宜之计 发表于 2025-3-24 16:17:31

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Armada 发表于 2025-3-24 19:22:39

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决定性 发表于 2025-3-24 23:53:14

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查看完整版本: Titlebook: Optimization-based Molecular Dynamics Studies of SARS-CoV-2 Molecular Structures; Research on COVID- 1 Jiapu Zhang Book 2023 The Editor(s)