单独 发表于 2025-3-23 10:25:53
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http://reply.papertrans.cn/71/7014/701356/701356_12.pngJocose 发表于 2025-3-23 18:08:46
The , family of nuclear proto-oncogenes c-., the senior member of this group of genes, is among the best studied of all cellular genes; N-., the next gene to be discovered, established the existence of genes closely resembling c-. in the mammalian genome; L-., the third gene of the group to be described, confirmed some of the . familial去掉 发表于 2025-3-24 01:11:48
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The epidermal growth factor receptor and its ligandsgulated interaction with the surrounding environment. Polypeptide growth factors and their receptors constitute one such pathway by which cells interpret the external milieu. Acting via specific membrane-spanning moieties, these messengers initiate a cascade of enzymatic activities which lead to repIntact 发表于 2025-3-24 13:03:38
The platelet-derived growth factor systemll proliferation in the setting of vascular injury and wound healing . It has become clear, however, that PDGF and its receptors (the PDGF system) play equally important roles in normal developmental and pathological processes, as well as in the genesis of certain neoplasms. In this respect, th灯泡 发表于 2025-3-24 15:48:13
Transforming growth factors-α and -β and their potential roles in neoplastic transformationsformation when added to an immortalized nonneoplastic cell line. One of these, TGF-α, is structurally related to epidermal growth factor (EGF) and competes for binding to the same receptor, while the other one, TGF-β, is a structurally unrelated protein with distinct receptors.抗体 发表于 2025-3-24 21:23:01
Oncogenes in human solid tumorsom the identification of oncogenes and their cellular counterparts, proto-oncogenes, as well as recessive anti-oncogenes, or tumor-suppressor genes. These general topics have been extensively reviewed . The purpose of this chapter is to address what is known about oncogene abnormalities in speBROOK 发表于 2025-3-25 00:34:12
Oncogenes in human leukemias and lymphomas to the wealth of knowledge on the growth and differentiation of the hematopoietic elements. Since malignancy is due to perturbations in the control of growth and differentiation, it is hoped that identifying genetic elements that induce leukemias may also point to those factors that control normal