Corticosteroids
发表于 2025-3-21 18:59:31
书目名称Oligonucleotide-Based Therapies影响因子(影响力)<br> http://impactfactor.cn/if/?ISSN=BK0700863<br><br> <br><br>书目名称Oligonucleotide-Based Therapies影响因子(影响力)学科排名<br> http://impactfactor.cn/ifr/?ISSN=BK0700863<br><br> <br><br>书目名称Oligonucleotide-Based Therapies网络公开度<br> http://impactfactor.cn/at/?ISSN=BK0700863<br><br> <br><br>书目名称Oligonucleotide-Based Therapies网络公开度学科排名<br> http://impactfactor.cn/atr/?ISSN=BK0700863<br><br> <br><br>书目名称Oligonucleotide-Based Therapies被引频次<br> http://impactfactor.cn/tc/?ISSN=BK0700863<br><br> <br><br>书目名称Oligonucleotide-Based Therapies被引频次学科排名<br> http://impactfactor.cn/tcr/?ISSN=BK0700863<br><br> <br><br>书目名称Oligonucleotide-Based Therapies年度引用<br> http://impactfactor.cn/ii/?ISSN=BK0700863<br><br> <br><br>书目名称Oligonucleotide-Based Therapies年度引用学科排名<br> http://impactfactor.cn/iir/?ISSN=BK0700863<br><br> <br><br>书目名称Oligonucleotide-Based Therapies读者反馈<br> http://impactfactor.cn/5y/?ISSN=BK0700863<br><br> <br><br>书目名称Oligonucleotide-Based Therapies读者反馈学科排名<br> http://impactfactor.cn/5yr/?ISSN=BK0700863<br><br> <br><br>
Osmosis
发表于 2025-3-21 21:52:09
Tissue-Specific Delivery of Oligonucleotidesl to the current CRISPR-Cas9 system offering gene editing at the genomic level, oligonucleotides, in addition to their biological functions in storing and conveying genetic information, provide the most prominent solutions to targeted gene therapies. Nonetheless, looking into the future of curing ca
CHECK
发表于 2025-3-22 03:31:19
Designing siRNA and Evaluating Its Effect on RNA Targets Using qPCR and Western Blotunderstanding of gene function. Carefully designed siRNAs can considerably improve siRNA specificity leading to more accurate and efficient gene silencing. Evaluation of gene knockdown is vital for optimization of siRNA efficacy. Here we describe the fundamental principles of siRNA design and strate
贪婪地吃
发表于 2025-3-22 08:31:31
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Notorious
发表于 2025-3-22 12:46:32
Assessing Oligonucleotide Binding to Double-Stranded DNAc approaches. Several methods can be used to evaluate ONs effect and binding capacity to their target sequence. Here we describe some of the methods, which have been frequently used for assessing ONs binding to dsDNA.
refraction
发表于 2025-3-22 13:27:38
Modeling and Simulation of Oligonucleotide Hybrids: Outlining a Strategyres of biomolecules. Effects of chemical modifications and of the environment such as sequence, solvent, and ionic strength can explicitly be taken into account. Molecular simulation techniques can also provide insight in change in binding affinity, in protonation (p. shift) and tautomeric propensit
屈尊
发表于 2025-3-22 18:09:09
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600
发表于 2025-3-22 22:12:27
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Liability
发表于 2025-3-23 02:59:35
Attachment of Peptides to Oligonucleotides on Solid Support Using Copper(I)-Catalyzed Huisgen 1,3-Di ONs with cell penetrating, homing or endosomal escape peptides can enhance specificity and/or uptake efficiencies. We describe here a general procedure for the preparation of peptide–oligonucleotide conjugates (POCs) on solid support utilizing a novel activated alkyne containing linker which enhanc
小平面
发表于 2025-3-23 08:11:32
Characterizing Oligonucleotide Uptake in Cultured Cells: A Case Study Using AS1411 Aptamer of the target. The therapeutic potential of oligonucleotides targeted to intracellular molecules will depend largely on their ability to be taken up by the cells of interest, as well as their subsequent subcellular distribution. Here we describe methods to characterize the extent and mechanism of c