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Chromatin Structure and Transcription,chromatin fiber, and finally the folding of the fiber into yet more complex structures. This compaction of DNA presents many impediments for .acting factors seeking access to the double helix. Many studies have sought insight into how this access might be achieved for proteins directing metabolic prhermetic 发表于 2025-3-22 04:04:05
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Reverse Gyrase,mperatures up to 100 °C, it is the first example of an ATP-dependent type I topoisomerase. Although it was isolated from hyperthermophiles, organisms considered by several authors as very primitive, close to the root of the tree of life (Woese et al. 1990; Olsen et al. 1994), reverse gyrase appearsConsensus 发表于 2025-3-22 16:43:07
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The Structure of the HMG Box and Its Interaction with DNA,ve of the DNA, e.g. the homeobox, zinc finger and bZIP/bHLH motifs. The HMG box differs from these domains in three important respects: (1) the principle contacts are to the minor groove, (2) a considerable bend is introduced into the DNA on binding and (3) there is wide variation in the DNA sequenc