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Luigi Silvestro,Simona Rizea Savu,P. A. van Veelen,P. L. Jacobs what’s considered to be “molecular targeted” versus convent.Folate pathways are essential in metabolism and macromolecule synthesis. Antifolate drugs that are largely transported via a high capacity folate transporter (i.e. the reduced-folate carrier) and inhibit folate-dependent enzymes include thcomely 发表于 2025-3-30 06:54:10
Günter Huhle,Job Harenberg,Reinhard Malsch,Dieter L. Heenensporter (i.e. the reduced-folate carrier) and inhibit folate-dependent enzymes include the dihydrofolate reductase inhibitor, methotrexate, and the thymidylate synthase inhibitors, raltitrexed and pemetrexed. Major advances in folate research made within the last decade include (i) the approval of