暗指 发表于 2025-3-27 00:43:01
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Dendrimers as DNA Carriers conjugates for DNA and ODN delivery in vitro and in vivo..Recently, other biologically functional small nucleic acids, such as small interfering RNA and micro RNA, have been developed for clinical applications. Dendrimers may be useful as carriers for these small RNAs. In fact, we have shown the us曲解 发表于 2025-3-27 08:37:21
An Oligonucleotide Carrier Based on β-1,3-Glucans this carrier compared to other cation types is that the driving force of the complexation is hydrogen bonds instead of electrostatic forces. Therefore, the total charge of the SPG/nucleotide complex is negative and there is no DNA-compaction problem in this system. Using chemically modified SPG, th缝纫 发表于 2025-3-27 12:20:36
http://reply.papertrans.cn/67/6672/667159/667159_34.png多余 发表于 2025-3-27 17:06:21
Active Transport of Exogenous Genes into the Nucleusmmalian cells, factors concerning nucleocytoplasmic transport have steadily been identified. As a result, significant progress has been made in the development of non-viral gene delivery systems capable of nuclear import. Currently, two approaches to active nuclear import of DNA are available. One i玉米 发表于 2025-3-27 18:10:25
Functional Nucleotide Sequences Capable of Promoting Non-viral Genetic Transferhnology (Vijayanathan et al. 2002). Employment of functional genetic elements, such as EBNA1/oriP and the . transposon, may further improve their efficacy, compensating for the shortcomings of non-viral systems. EBV-based plasmid vectors are transported into and maintained in the nucleus as well asCLASH 发表于 2025-3-27 22:57:20
Mahito Nakanishi IMRT, IGRT, motion management, SBRT), (2) a shift away from elective nodal irradiation towards restriction to the primary tumour only. All of the above described changes have been introduced over time and they have not formally been tested as primary endpoints in dedicated trials. This leaves room愤怒事实 发表于 2025-3-28 03:00:58
http://reply.papertrans.cn/67/6672/667159/667159_38.png可触知 发表于 2025-3-28 06:48:04
Hidetaka Akita,Ikramy A. Khalil,Kentaro Kogure,Hideyoshi Harashimaon and purpose are entirely practical, in that the focus is on the physics essentials of delivery and treatment planning , illustration of the clinical target volume (CTV) and associated treatment planning for each major malignancy when using particle therapy, proton therapy in particular. Disease-nonplus 发表于 2025-3-28 12:58:17
Takeshi Nagasaki which clinicians and the treatment planning team should pay.This handbook is designed to enable radiation oncologists to treat patients appropriately and confidently by means of particle therapy. The orientation and purpose are entirely practical, in that the focus is on the physics essentials of d