emission 发表于 2025-3-27 01:01:31
Cellular Signal Transduction and Nitric Oxideignaling elements, including the phospholipase C/calcium signaling systems, tyrosine kinase signaling pathways, G-proteinlinked receptors, ion channels, cyclic guanosine monophosphate (cGMP) and cyclic adenosine monophosphate (cAMP)-dependent pathways, and the apoptotic pathway. Traditionally, nitriFlounder 发表于 2025-3-27 03:59:59
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Cytotoxicity, Apoptosis, and Nitric Oxidedeath by injury also contributes to various pathophysiological disorders. Toxic insults or ischemic injury can lead to the destruction of cells. Such cytotoxic effects are often the consequence of necrotic cell death. Necrotic processes are characterized by the disruption of cell homeostasis, energyApraxia 发表于 2025-3-27 10:47:29
Nitric Oxide and Ion Channelsgulation of vascular tone (Table 1 provides a list of all abbreviations used in this chapter). Ion channels regulate not only vessel contraction, but also relaxation to nitric oxide (NO.) and nitrovasodilators. This chapter summarizes the present knowledge of the mechanisms by which NO. affects distfastness 发表于 2025-3-27 14:56:51
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Nitric Oxide and Platelet-Mediated Hemostasis (.). Under resting conditions, blood flow stimulates the endothelium to produce NO., which regulates platelet activity (.). NO. activates soluble guanylyl cyclase leading to a concomitant increase in the production of cyclic guanosine monophosphate (cGMP), the principal mediator of NO. s effects. A歪曲道理 发表于 2025-3-28 01:47:42
Nitric Oxide Modulates Leukocyte—Endothelial Cell Adhesionlarge body of recent evidence that implicates leukocytes in a number of other pathological conditions, including atherosclerosis, hypertension, ischemia—reperfusion injury, venous thrombosis, and gastric ulceration. The recognition that a leukocyte must first adhere to vascular endothelium before it傲慢物 发表于 2025-3-28 02:47:12
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The Fibroblast and Nitric Oxide synthesis of the extracellular matrix proteins including collagen, elastin, and reticular fibers, as well as the complex carbohydrates of the ground substance. In addition, during pathophysiological processes such as wound healing, the fibroblast can change phenotype, differentiate into a myofibrobarrhythmic 发表于 2025-3-28 11:49:01
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