Encounter
发表于 2025-3-21 18:17:35
书目名称Nitrates III影响因子(影响力)<br> http://impactfactor.cn/if/?ISSN=BK0666623<br><br> <br><br>书目名称Nitrates III影响因子(影响力)学科排名<br> http://impactfactor.cn/ifr/?ISSN=BK0666623<br><br> <br><br>书目名称Nitrates III网络公开度<br> http://impactfactor.cn/at/?ISSN=BK0666623<br><br> <br><br>书目名称Nitrates III网络公开度学科排名<br> http://impactfactor.cn/atr/?ISSN=BK0666623<br><br> <br><br>书目名称Nitrates III被引频次<br> http://impactfactor.cn/tc/?ISSN=BK0666623<br><br> <br><br>书目名称Nitrates III被引频次学科排名<br> http://impactfactor.cn/tcr/?ISSN=BK0666623<br><br> <br><br>书目名称Nitrates III年度引用<br> http://impactfactor.cn/ii/?ISSN=BK0666623<br><br> <br><br>书目名称Nitrates III年度引用学科排名<br> http://impactfactor.cn/iir/?ISSN=BK0666623<br><br> <br><br>书目名称Nitrates III读者反馈<br> http://impactfactor.cn/5y/?ISSN=BK0666623<br><br> <br><br>书目名称Nitrates III读者反馈学科排名<br> http://impactfactor.cn/5yr/?ISSN=BK0666623<br><br> <br><br>
农学
发表于 2025-3-21 22:22:25
Comparative Haemodynamic and Pharmacokinetic Investigations After Oral Isosorbide-2-mononitrate and The metabolites isosorbide-2-mononitrate (IS-2-MN) and 5-mononitrate (IS-5-MN) are demonstrable in the plasma for several hours at concentrations which are but slowly decreasing, in contrast to those measured after oral isosorbide dinitrate, (ISDN) .
Pander
发表于 2025-3-22 01:36:09
Newer Methods of Administration of Nitrates to Man to Give a More Predictable Therapeutic ResponseIsosorbide dinitrate (ISDN) given orally is extensively metabolised by “first pass” metabolism, less than 3% appearing unchanged in the blood using this route. However, the two mononitrate metabolites are active and thus probably contribute significantly to the observed effects when ISDN is given orally.
菊花
发表于 2025-3-22 07:01:54
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eucalyptus
发表于 2025-3-22 09:59:16
Induction and Inhibition of Organic Nitrate MetabolismOrganic nitrate vasodilators, such as glyceryl trinitrate (GTN) or isosorbide dinitrate (ISDN), are denitrated by the glutathione (GSH) S-transferases (EC 2.5.1.18) according to the general scheme :RONO.+GSH→RHO+HNO.+GSSG.
terazosin
发表于 2025-3-22 13:32:01
978-3-642-68087-8Springer-Verlag Berlin Heidelberg 1981
neurologist
发表于 2025-3-22 20:49:27
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积习难改
发表于 2025-3-22 23:49:07
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Confound
发表于 2025-3-23 05:16:13
Fate of Isosorbide Mononitrates in Manegimen, the duration of action, and the relationship between plasma concentration and effect are still under discussion. In an attempt to solve some of these problems, a pharmacologic and/or therapeutic role for the nitrated metabolites of substances such as glyceryl trinitrate and isosorbide dinitrate has been postulated.
指令
发表于 2025-3-23 08:40:40
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