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Komate Amphawan,Philippe Lenca,Athasit Surarerksearrangements or to fork collapse followed by cell death. Consequently, DNA damage is dangerous for replicating cells. What happens when DNA damage appears after a replication round has been successfully finished? Various DNA lesions may disturb the transcription efficiency of the affected genes. DN北极熊 发表于 2025-3-25 14:53:14
Hailin Li,Chonghui Guo,Libin Yangion have placed p53 at the center of cancer investigation. Numerous cellular and mouse models have demonstrated that restoration of p53 function may stop tumor progression or even promote tumor regression. Now, these observations lead to the development of multiple anti-cancer therapeutic strategies斜 发表于 2025-3-25 17:44:37
Vo Le Quy Nhon,Duong Tuan Anhe molecules, have been developed. Most of them are excellent tools to characterize better the emerging molecular mechanisms regulating distinct critical cellular processes. Some of them have been launched already while many others are still in pre-clinical development. This chapter updates some of t脱离 发表于 2025-3-25 22:12:29
Masahiro Ishikawaseeks to aid scientists to further study multiple stress pathways and outcomes triggered by such stresses. In depth knowledge of cellular stress will eventually lead to the development of novel therapeutics to prevent or treat related diseases..978-1-4939-4848-2978-1-4939-2522-3Series ISSN 1064-3745 Series E-ISSN 1940-6029讥笑 发表于 2025-3-26 01:44:17
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Anca Maria Ivanescu,Marc Wichterich,Thomas SeidlSB repair. Therefore, methods to quantitatively or semiquantitatively assess DNA end resection have gained importance in laboratories working on DNA repair. In this chapter, we describe two simple immunofluorescence-based techniques to monitor DNA end resection in mammalian cells. The first techniquPANG 发表于 2025-3-26 15:16:12
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