Objective 发表于 2025-3-21 18:02:55
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Pharmacology and clinical investigation of SR-2508 (etanidazole)he abnormal metabolic environment of solid tumors. It is proposed that the disordered vascular development in the growing tumor mass results in a proportion of cells being remote from capillaries; the increased diffusion distance leads to hypoxia, low glucose concentrations, and reduced cellular pH凝视 发表于 2025-3-22 07:47:25
Folate antimetabolites inhibitory to , purine synthesisalogs that were more active than methotrexate or, at least, that had different properties than this important folate antimetabolite. After 40 years of preclinical and clinical investigation, methotrexate is still in clinical use and still represents the only folate analog in widespread therapeutic aenumaerate 发表于 2025-3-22 09:54:39
Taxol: A new agent active in melanoma and ovarian cancercharacterized by Wani et al. . This drug is a complex ester,consisting of a taxane derivative with an oxetan ring, an unusual chemical structure (as shown in figure 1) whose biological activity had not been previously studied.plasma-cells 发表于 2025-3-22 13:33:43
ICRF-187 (ADR-529) cardioprotection against anthracycline-induced cardiotoxicity: Clinical and preclronic dose-dependent cardiomyopathy. The ability of anthracyclines to induce a chronic dose-dependent cardiomyopathy has been well documented. A number of approaches to abrogate this effect have been explored with varying degrees of success. These include the development of analogs of the parent ant欢笑 发表于 2025-3-22 17:54:27
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andererseits verschwinden aber auch Märkte, Intermediäre bzw. Lieferanten werden durch effizientere Prozesse stärker gebunden. Wo sich E-Commerce-Anwendungen etablieren, werden Wertschöpfungsstrukturen ganzer Industrien verändert. Die Transformationsprozesse sind durch vielfältige Interaktionen von陈旧 发表于 2025-3-23 08:46:25
John S. Holcenberg,Henry P. Wunelle Zahlungsmittel, wie beispielsweise die Rechnung und Überweisung. Dies hängt mit mangelndem Vertrauen in den elektronischen Handel (E-Commerce) zusammen. Ursachen hierfür sind die Charakteristika und Effekte elektronischer Marktplätze, die gekennzeichnet sind durch Unvollkommenheiten und Komple