战役
发表于 2025-3-28 18:40:38
The Growing Problem of New Psychoactive Substances (NPS),ive responses in a domain capable of overwhelming current international conventions and national drug control policies. Ultimately, research-guided prevention education will fortify societies against this tidal wave.
动物
发表于 2025-3-28 21:28:52
Structure-Activity Relationships of Synthetic Cathinones,as the nature of the terminal amine, the size of the α-substituent, stereochemistry, and the presence and position of aromatic substituents, are being found to impact action (i.e., as releasing agents or reuptake inhibitors) and transporter selectivity.
panorama
发表于 2025-3-29 00:50:51
Interactions of Cathinone NPS with Human Transporters and Receptors in Transfected Cells,merged as NPS that are extremely potent transporter inhibitors but not monoamine releasers. Cathinones exhibit clinically relevant differences in relative potencies at serotonin vs. dopamine transporters. Additionally, cathinone NPS have more dopaminergic vs. serotonergic properties compared with th
fiscal
发表于 2025-3-29 05:16:31
Electrophysiological Actions of Synthetic Cathinones on Monoamine Transporters,ent outward currents by blocking an inherent inward leak current. We have employed the two-electrode voltage-clamp technique in . oocytes overexpressing monoamine transporters to determine whether synthetic cathinones found in the so-called bath salts products behave as blockers or substrates. We al
MIME
发表于 2025-3-29 09:41:46
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single
发表于 2025-3-29 12:20:38
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发酵
发表于 2025-3-29 19:34:58
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Charitable
发表于 2025-3-29 22:35:08
MDMA, Methylone, and MDPV: Drug-Induced Brain Hyperthermia and Its Modulation by Activity State andhe brain due to metabolic brain activation and diminished heat dissipation due to peripheral vasoconstriction as two primary contributors to the hyperthermic effects of these drugs. Then, we will consider how the hyperthermic effects of these drugs are modulated under conditions that model human dru
anaphylaxis
发表于 2025-3-30 00:32:59
Neurotoxicology of Synthetic Cathinone Analogs,xic properties are not abundant. The biochemical gauges of neurotoxicity induced by non-keto analogs are well studied in humans and experimental animals and include their ability to induce neuroinflammation, oxidative stress, excitotoxicity, temperature alterations as well as dysregulation of neurot
间接
发表于 2025-3-30 05:50:30
,Combination Chemistry: Structure–Activity Relationships of Novel Psychoactive Cannabinoids,en tested, have been shown to activate these receptors and to produce a characteristic profile of effects, including suppression of locomotor activity, antinociception, hypothermia, and catalepsy, as well as Δ.-tetrahydrocannabinol (THC)-like discriminative stimulus effects in mice. When they have b