mature 发表于 2025-3-21 19:26:29
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,Selegiline Induces “Trophic-Like” Rescue of Dying Neurons without MAO Inhibition, It is controversial whether the slowing represents a symptomatic action due to improved dopaminergic neurotransmission or neuroprotection due to a decrease in the production of toxic oxidative radicals consequent on the inhibition of monoamine oxidase B (MAO-B). We propose a third action for selegi记忆 发表于 2025-3-22 01:57:51
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,Medical Treatment of Parkinson’s Disease,opamine (DA) deficiency. L-dopa + peripheral amino acid decarboxylase inhibitor (DDI: Sinemet or Madopar) is still the most effective agent for the symptomatic treatment of PD, but the dopa therapy is far from perfect. For advanced cases especially for patients with wearing off of the drug effect, fMediocre 发表于 2025-3-22 09:58:59
Neurotoxicity of MPTP and Uptake of MPPT into Dopamine and Norepinephrine Neurons in Mice,gra (SN) and norepinephrine (NE) neurons in the locus coeruleus (LC) other than in the terminals. These results suggest that DA neurons in the SN and NE neurons in the LC are possibly able to uptake MPP. through the DA and NE uptake systems, respectively, presumably via DA and NE dendrites. The pres压舱物 发表于 2025-3-22 13:58:03
Linopirdine,ence. Alzheimer’s disease (AD), the leading cause of dementia in the aged population, is devastating to the patients as well as their family members. This is a costly disease to the individuals and to society. Although an enormous effort is being made to understand the cause of this disease and to dBAN 发表于 2025-3-22 18:40:22
Differential Changes in Regional Brain Ganglioside and Neutral Glycosphingolipid Contents in Alzheis characterized histopathologically by the intraneuronal accumulation of neurofibrillary tangles, deposits of neuritic plaques in the neuropil, and neuronal loss in specific regions of the forebrain.. Neurochemically, multiple transmitter deficits in autopsy brain tissues have been reported.. SinceNADIR 发表于 2025-3-22 23:04:39
Action of Organophosphate Anticholinesterases on the Three Conformational States of Nicotinic Recepethylphosphonofluoridate), sarin (isopropyl methylphosphonofluoridate, tabun (ethyl N-dimethylphosphoramidocyanidate) and phencyclidine did not show any effect on the binding of [.I]α-cobrotoxin to the nicotinic receptor. However, VX, O-ethyl-S-(2-diisopropylaminoethyl) methylphosphonothiolate, at cOratory 发表于 2025-3-23 04:54:53
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