FEAS
发表于 2025-3-27 00:39:29
Neuroblastoma: Ornithine Decarboxylase and Polyamines are Novel Targets for Therapeutic Interventionnd a FDA-approved Phase I NB clinical trial with DFMO alone and combined with etoposide is currently underway. Given the current lack of effective therapies, the identification of novel and innovative combination therapies is paramount in the endeavour to combat this aggressive paediatric malignancy
LAY
发表于 2025-3-27 03:21:36
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Organization
发表于 2025-3-27 05:25:39
Neuroblastoma: Perspectives for the Use of IL-21 in Immunotherapyhich may limit the efficacy of IT. The co-administration of an anti-CD25 monoclonal antibody (mAb), targeting immune-suppressive CD4+CD25+FoxP3+ regulatory T (Treg) cells, slightly augmented the efficacy of IL-21-based IT. However, an anti-CD4 mAb combined with the vaccine produced an even higher cu
NORM
发表于 2025-3-27 09:30:35
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ellagic-acid
发表于 2025-3-27 14:05:13
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凶残
发表于 2025-3-27 21:00:53
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coagulate
发表于 2025-3-28 01:34:06
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Lacunar-Stroke
发表于 2025-3-28 03:45:31
Introductionrs in 1 in 100,000 children, and is diagnosed in ∼650 children each year in the United States. It accounts for 7–8% of childhood cancers. It is an extracranial pediatric tumor, and occurs when immature nerve cells (neuroblasts) become abnormal and multiply uncontrollably to form a tumor. The tumor o
寄生虫
发表于 2025-3-28 09:16:08
Pediatric CNS Neuroblastoma: Magnetic Resonance Imaging and Spectroscopyremely rare and may involve the cerebral parenchyma, leptomeninges, or dura. Magnetic resonance imaging (MRI) plays an important role in the initial diagnosis and staging of neuroblastoma as it provides for accurate tumor localization, size, extent and metastases. The technique aids image-guided sur
单色
发表于 2025-3-28 11:36:14
Pediatric Neuroblastoma-Associated Opsoclonus-Myoclonus-Ataxia Syndrome: Early Diagnosise of multiples neurological and developmental signs and symptoms to the presence of an occult neuroblastoma. Given the rarity of disease, diagnosis could be challenging. Despite immunosuppressive treatment, neurodevelopmental long-term prognosis is poor and persisting disability is present in most c