厨房默契 发表于 2025-3-21 19:39:27
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Antagonists of Folic Acid and Vitamin B6 in Regulation of S-Adenosylmethionine and S-Adenosylhomocyzone) and related compounds is due to the inhibition of SAM decarboxylase (EC 4.1.1.50) in malignant tissue. The antitumor activity of cycloleucine (the conformational analogue of L-methionine) was suggested to be due to inhibition of L-methionine conversion to SAM catalyzed by SAM synthetase (EC 2.5.1.6)..staging 发表于 2025-3-22 04:18:01
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Methylase Mechanisms: Steric Constraints and Modes of Catalysis,ith more recent results of our chemical mechanism studies. Ultimately, we would like to use this information in the design of potent, specific multisubstrate adduct (“transition state analog”) inhibitors (3) of these reactions.organism 发表于 2025-3-22 13:11:21
Adenosylmethionine as a Precursor for Nucleic Acids Modification,e transfer of both the adenosyl moiety and of the 3-amino-3-carboxypropyl group have been described in very few instances.: the acceptor molecules are enzyme proteins for the adenosyl moiety., and transfer RNA (tRNA) for the 3-amino-3-carboxypropyl group..过份 发表于 2025-3-22 17:15:51
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Involvement of S-Adenosylmethionine in Brain Phospholipid Metabolism,hway, first demonstrated in liver by Bremer and Greenberg. and successively described in this tissue by several authors, has not been however unequivocally demonstrated in brain, and conflicting data have been produced in this connection..DAFT 发表于 2025-3-23 07:14:50
Homocysteine Biosynthesis in Plants,s eventually to inorganic sulfate. Plants complete the cycle of sulfur by reductive assimilation of inorganic sulfate to methionine (and cysteine) (Siegel, 1975), and are thus the ultimate source of methionine in most animal diets.