LAY 发表于 2025-3-26 22:55:49

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心胸狭窄 发表于 2025-3-27 02:21:38

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Ointment 发表于 2025-3-27 06:02:16

High-Throughput Functional Detection of NMDA Receptor Activity,ificity. The increasing number of entities in pharmaceutical company compound libraries, frequently surpassing 10., dictates the use of a high-throughput screening (HTS) process. In practice, large numbers of individual compounds are quickly tested for their ability to interact with, and affect a ch

柔美流畅 发表于 2025-3-27 12:22:10

The Use of Ligand Binding in Assays of NMDA Receptor Function,and to use because of nonspecific binding. The identification of MK801 (dizocilpine) and thienylphencyclidine (TCP) as highly potent and very selective inhibitors of NMDA receptor function (.–.) brought the possibility of ligand binding to NMDA receptors into the mainstream.

非秘密 发表于 2025-3-27 16:38:15

NMDA Receptor Pharmacology and Analysis of Patch-Clamp Recordings,evel can be used as a basis for comparison with whole-cell concentration-response curves. This procedure allows the investigator to compare the effects of a variety of drugs at the molecular level using a well-established set of tools developed for analysis of macroscopic responses.

instulate 发表于 2025-3-27 18:43:03

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Charlatan 发表于 2025-3-28 00:46:08

Expression of Extracellular N-Terminal Domain of NMDA Receptor in Mammalian Cells,, and polyamines (.). The NR1 subunit consists of two functionally distinct regions: a large amino-terminal extracellular domain containing the putative agonist binding site and a hydrophobic core consisting of four transmembrane-spanning domains that participate in the formation of the ion-conducting pathway.

美学 发表于 2025-3-28 05:56:19

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AXIOM 发表于 2025-3-28 06:51:51

Book 1999g assays for nontherapeutic lead selection. The topics range from cDNA cloning to in vitro and in vivo investigation of the channel complex in the mammalian brain. Additional topics include the biochemical analysis of the channel protein and the construction of various heterologous systems for both

不可知论 发表于 2025-3-28 11:53:36

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查看完整版本: Titlebook: NMDA Receptor Protocols; Min Li Book 1999 Humana Press 1999