endure
发表于 2025-3-25 06:01:29
http://reply.papertrans.cn/67/6602/660113/660113_21.png
Euphonious
发表于 2025-3-25 08:07:06
http://reply.papertrans.cn/67/6602/660113/660113_22.png
先驱
发表于 2025-3-25 13:35:35
,The NF-κB Signaling Pathway: Players and Functions,tivation exist, a canonical one and a non-canonical one, both of them requiring intricate molecular interplays involving adaptor proteins and enzymes that control phosphorylation and ubiquitination events. This culminates in translocation of NF-κB in the nucleus and modulation of gene expression.
Directed
发表于 2025-3-25 17:21:09
,Genetic Diseases Affecting Ubiquitination Processes in NF-κB Signaling,ain formation; TRAF6, a key regulator in immunity and skin appendages development; and CYLD, a deubiquitinase negatively regulating the NF-κB activation process at several levels. They provide an alternative entry point to analyze the consequences of deregulated NF-κB activity.
斗志
发表于 2025-3-25 21:53:17
http://reply.papertrans.cn/67/6602/660113/660113_25.png
Communal
发表于 2025-3-26 00:13:40
,Lessons Learned from Studying NF-κB-Related Genetic Diseases, for the same components and, on the other, to assign specific defects in humans to discrete molecular impairments. All these information should contribute to the design and validation of therapeutic treatments.
跳脱衣舞的人
发表于 2025-3-26 07:50:51
Book 2016ted pathologies affecting the components of the NF-KB signaling pathway offers the opportunity to understand the various functions of NF-KB in humans, complementing studies performed with mouse models. In addition, people treating those patients acquire a deeper understanding of the molecular basis
Sad570
发表于 2025-3-26 12:23:08
http://reply.papertrans.cn/67/6602/660113/660113_28.png
羊齿
发表于 2025-3-26 16:19:55
,Genetic Diseases Affecting the Canonical Pathway of NF-κB Activation, pathologies caused by mutations of NF-κB subunits regulating exclusively the canonical pathway. They allowed to confirm the essential role of canonical NF-κB activation in innate and acquired immunity or inflammation but also revealed new functions of this pathway.
floaters
发表于 2025-3-26 18:16:46
http://reply.papertrans.cn/67/6602/660113/660113_30.png