Heterodoxy 发表于 2025-3-25 05:36:01
Daniel Nagel,Daniel Krappmannated text and discourse analysis.Reviews the state of the ar.This book revisits discourse analytic practice, analyzing the idea that the field has access to, provides, or even constitutes a ‘toolbox’ of methods. The precise characteristics of this toolbox have remained largely un-theorized, and theinflame 发表于 2025-3-25 10:11:37
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Measurement of NF-κB Transcriptional Activity and Identification of NF-κB ,-Regulatory Elements Usinmmunoreceptors such as the Toll-like receptors, cytokine receptors, and antigen receptors, growth factors, survival factors, and stress signals such as ultraviolet irradiation and oxidative stress. The transcriptional targets of these various pathways include approximately 500 experimentally indentiBrochure 发表于 2025-3-25 21:08:27
Assessing Sites of NF-κB DNA Binding Using Chromatin Immunoprecipitationsion of hundred of genes of importance to a range of physiological and pathological processes. The binding of NF-κB to the regulatory regions and promoters of target genes is influenced by a number of factors including the sequence of DNA-binding sites, the posttranslational modification of NF-κB, aABASH 发表于 2025-3-26 03:55:14
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Analysis of Epidermal Growth Factor-Induced NF-κB Signalingory responses, and innate and adaptive immune responses. Its activation is tightly regulated, and incorrect regulation of NF-κB has been linked to a variety of pathological diseases, including cancer initiation and progression. NF-κB is often constitutively activated in cancer cells to promote cellrods366 发表于 2025-3-26 09:50:13
Methods to Assess the Activation of the Alternative (Noncanonical) NF-κB Pathway by Non-death TNF Recalled processing) of the precursor p100 into p52. This pathway is activated by a subset of non-death TNF receptor members, which ultimately activate two kinases: NIK (NF-κB-Inducing Kinase) and IKKα (Inhibitor of κB Kinase alpha). These kinases create a phosphodegron for the E3 ligase SCF-β-TrCP thentail 发表于 2025-3-26 16:11:44
Systematic Detection of Noncanonical NF-κB Activationp100, the precursor of NF-κB2 mature form p52. Accordingly, there are two major mechanisms leading to NF-κB activation: inducible degradation of IκBs and processing of p100 to generate p52 (selective degradation of the C-terminal IκB-like sequence of p100), which are termed the canonical and noncanoFacet-Joints 发表于 2025-3-26 18:55:14
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