连锁 发表于 2025-3-26 21:00:05
A New View on the Mechanism of Action of Reversible Cholinesterase Inhibitors as Drugs for Prophylaxe, in conjunction with atropine and oxime, gave appreciable protection against poisonings by any OP, including soman (4, 5, 6). Since 1946 when G. Koster had showed the protective effect of physostigmine against DFP poisoning, the mechanism of the prophylactic action of RI was connected only with an集合 发表于 2025-3-27 03:06:23
Cholinesterases as Bioscavengers for Protection Against Organophosphate Chemical Warfare Agents be effective bioscavengers against a variety of OP compounds in rodents as well as non-human primates. Pretreatment of rhesus monkeys with fetal bovine serum (FBS) AChE or horse and human serum butyrylcholinesterase (BChE) protected them against a challenge of up to 5 LD. of soman (O-pinacolyl meth深陷 发表于 2025-3-27 05:17:16
Reactivators, from Classic to a New Generation with OPC. We consider the importance of the evaluation of pharmacokinetics of the reactivators as well as changes on background of intoxications with different kinds of OPC, as well as of the toxicokinetics of OPC after treatment. It is important that before the synthesis of some new compounds, toIRATE 发表于 2025-3-27 12:21:55
Treatment of Organophosphate Nerve Agents, Current Therapy and Future Prospectives improvements in survival from nerve agent poisoning in a number of species, including primates. As the result of use in the Gulf War, the safety of pyridostigmine has been an ongoing topic of debate. Since our continued use of pyridostigmine in the future depends on the demonstration of its safety,吹牛需要艺术 发表于 2025-3-27 16:12:38
Reactivation of Organophosphorus — Inhibited Human Erythrocyte-Acetylcholinesterase by Oximes in vitibited AChE by oximes was dependent on the organophosphate used. After soman, sarin, cyclosarin or VX the reactivation increased in the order HLö 7 > HI-6 > obidoxime > pralidoxime. Only obidoxime and HLö 7 reactivated tabun inhibited AChE partially, while pralidoxime and HI-6 were almost completelyAcclaim 发表于 2025-3-27 19:15:08
http://reply.papertrans.cn/67/6601/660078/660078_36.pngphlegm 发表于 2025-3-27 23:28:52
Testing the Antidotal Efficiency in the Treatment of Aflatoxin Poisoninges of vitamin A orally, irrespective of the posology, partially protect the animal against aflatoxins and dicreases mortality to less than half..We recommend that prophylactic or therapeutic carotenoids can be administered to persons exposed to aflatoxins.等级的上升 发表于 2025-3-28 05:18:54
Book 1999le and all the participants of the conference who contributed their publications. In particular, the editors would like to thank Constantin Mircioiu and his staff for their assistance and support during all stages of the conference and editing. In addition, they are grateful to Harald Kempf and hiscommitted 发表于 2025-3-28 09:39:16
L. Szinicz,H. Thiermann,P. Eyer,T. Zilkerlitated..Even though optical methods for measuring membrane potential were introduced relatively recently, their uses have multiplied rapidly and will doubtless continue to proliferate. It seems likely that, in several instances, optical techniques will prove to be quite powerful and, used with caut首创精神 发表于 2025-3-28 11:28:06
Viorel Ordeanu,Victor A. Voicu,Angela Postoarca,Rodica Chiosila,Rodica Alexandrescu,Bogdan Circiumarlitated..Even though optical methods for measuring membrane potential were introduced relatively recently, their uses have multiplied rapidly and will doubtless continue to proliferate. It seems likely that, in several instances, optical techniques will prove to be quite powerful and, used with caut