吹气 发表于 2025-3-26 23:48:16
,Regulation of NAA-Synthesis in the Human Brain ,: Canavan’s Disease, Alzheimer’s Disease and SchizoIntrovert 发表于 2025-3-27 03:06:53
http://reply.papertrans.cn/67/6601/660005/660005_32.png有权 发表于 2025-3-27 06:52:27
Conference proceedings 2006er injury, or slowly during neurodegenerative diseases, MRS has become a preferred method of analyzing nerve cell dysfunction and death without surgical intervention. ..The second reason that NAA has attracted attention in recent years is that a congenital genetic disorder of NAA metabolism has been陈列 发表于 2025-3-27 13:25:54
A Brief Overview of ,-Acetylaspartate and ,-Acetylaspartylglutamate,rence will attract a broader interest in these moieties, as they have been linked to serious disorders including schizophrenia, Alzheimer’s Disease and pain. Given their remarkably high concentrations in the brain, the current level of research on NAAG and NAA seems to underestimate their potential significance.Conclave 发表于 2025-3-27 14:27:32
Conference proceedings 2006e of the most highly concentrated chemicals found in the brain of humans and animals, and yet the functions served by this brain-specific metabolite remain elusive, and controversial. Despite the uncertainties surrounding the functions of NAA in the development and operation of the nervous system, t形上升才刺激 发表于 2025-3-27 20:49:40
Canavan Disease: Studies on the Knockout Mouse,ular studies of the mouse brain showed abnormal expression of multiple genes in addition to ASPA deficiency. Adenoassociated virus mediated gene transfer and stem cell therapy in the knockout mouse are the latest attempts to alter pathophysiology in the CD mouse.AV-node 发表于 2025-3-27 22:31:56
Mutation Analysis of the Aspartoacylase Gene in Non-Jewish Patients with Canavan Disease,on-Jewish persons with Canavan disease requires sequencing of all exons and their splice sites as well as a search for insertions and deletions. When mRNA cannot be found so that cDNA is unavailable for sequencing, it may be possible to use polymorphisms in place of the actual mutations for prenatal diagnosis.准则 发表于 2025-3-28 02:15:42
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ylated form of the amino acid aspartate, and it is present exclusively in the nervous system. Indeed, NAA is one of the most highly concentrated chemicals found in the brain of humans and animals, and yet the functions served by this brain-specific metabolite remain elusive, and controversial. DespiFabric 发表于 2025-3-28 11:15:31
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