反感
发表于 2025-3-28 18:26:44
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muster
发表于 2025-3-28 20:48:58
Klaus Wolffluorescence lifetime imaging microscopy (FLIM) have proven to be robust and sensitive to determine Ras nanoclustering changes. Loss of FRET that emerges due to nanoclustering reports on all processes upstream of Ras nanoclustering, i.e., also on proper trafficking or lipid modification of Ras. Here
Ceramic
发表于 2025-3-28 23:03:33
ings and technical developments in the Ras field, leading to an improved insight into many aspects of Ras biology, they have not jolted at the basics, but rather deepened our view of the fundamental regulatory principles of Ras activity control. In this brief review, we revisit the role and mechanis
Simulate
发表于 2025-3-29 05:15:46
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洞穴
发表于 2025-3-29 10:21:32
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钝剑
发表于 2025-3-29 12:13:03
Willy Fachéfluorescence lifetime imaging microscopy (FLIM) have proven to be robust and sensitive to determine Ras nanoclustering changes. Loss of FRET that emerges due to nanoclustering reports on all processes upstream of Ras nanoclustering, i.e., also on proper trafficking or lipid modification of Ras. Here
ILEUM
发表于 2025-3-29 19:10:53
Wolfgang Kroner,Stephan Wolff genetic manipulations of the Ras–ERK pathway. The phenotypes of global mutants as Ras-GRF1 KO, GENA53, and ERK1 KO mice, as well as of conditional region-specific mutants (striatal K-CREB mice), will be illustrated as examples. Novel object recognition (NOR), developed by Ennaceur and Delacour in 1
Little
发表于 2025-3-29 21:58:50
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Intervention
发表于 2025-3-30 01:51:10
Pavel Uttitzolysis. Further, an interaction between Tyr35 and the nucleotide inhibits GTP hydrolysis, and mutation of this residue resulted in a tenfold increase in the intrinsic GTPase activity of Rheb. The protein product of the Tsc2 gene (hamartin) was identified as a GTPase activating protein (GAP) that ina
佛刊
发表于 2025-3-30 04:59:40
Helmut Gieglerons of the G domain are especially prone to crystallization artifacts. Regions that are mobile in solution are commonly “frozen out” into relatively arbitrary conformations that often are dictated by the specifics of the packing against neighboring molecules in the crystals. It requires very careful